WebThe USPSTF found that statins have a 0.46% absolute benefit (NNT = 217) for nonfatal heart attacks. 4 This NNT is probably artificially improved (lowered) by the predominance of events that occurred in high-risk individuals. WebAlendronate decreased the risk of radiographic vertebral fractures by 44% overall (relative risk, 0.56; 95% CI, 0.39-0.80; treatment-control difference, 1.7%; NNT, 60). Alendronate did not increase the risk of gastrointestinal or other adverse effects. Conclusions:
Romosozumab: A Review in Postmenopausal Osteoporosis
WebAlendronate is also used to treat osteoporosis in men and women who are taking corticosteroids (a type of medication that may cause osteoporosis in some patients). Alendronate is also used to treat Paget's disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). WebCons. Has to be taken with a full glass of plain water first thing in the morning 30 minutes before you eat, drink, or take other medications. Can cause serious jaw problems and severe muscle or joint pain. Has many stomach-related side effects. Must remain upright for 30 minutes after taking. robert m. price books
New national osteoporosis guidance—implications for geriatricians
WebMoreover, the NNT to avoid an additional major osteoporotic fracture at 5 years of treatment with alendronate when compared to SR within the CPRD and SIDIAP datasets was calculated to be 33 and 500, respectively. WebFeb 1, 2024 · Alendronate is used to prevent and treat osteoporosis (thinning of the bone) in women after menopause. This medicine may also be used to increase bone mass in … WebFeb 1, 2009 · Alendronate (Fosamax) 70 mg weekly: Oral: Hip, vertebral, nonvertebral: Tablet: $87, $77 (generic) Solution: $96: Ibandronate (Boniva) 150 mg monthly: Oral: … robert m. rifkin et al.2019 ash. poster 1882